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Advance Laboratory Medicine International
Periodical of WV publisher
Journal Home Page		ISSN: 2228-8961 (Print)
ISSN: 2228-8961 (Online)
Language: [ English ]  

  » Volume 3, Issue 2
      pp. 14-31
  » Volume 3, Issue 1
      pp. 1-13

 

Open Access

Case Report



Acute promyelocytic leukemia in four year-old child. A case report

Guido D'Angelo, Lorena Ceriani, Anna Maria Hotz, Daniela Mazzola, Roberta Ranalli.

A B S T R A C T 

Abstract
30% of pediatric oncohematologic malignancy are acute leukemias and in this area the AML incidence is very low, much less than the acute promyelocytic leukemia. We report the case of a 4 year old girl with acute promyelocytic leukemia whose blasts showed the morphology characteristic of acute promyelocytic leukemia variant and the Fluorescence In Situ Hybridization confirmed the presence of t(15;17) translocation. The case is reported because in the pediatric population the acute promyelocytic leukemia is a rare occurrence; moreover, it represent a true oncohematologic emergency, in this case the laboratory has a significant role since the timing of diagnosis must be very short.

Key words: Acute Promyelocytic Leukemia; t(15;17) traslocation; ATRA; ADVIA 2120i (Siemens Healthcare ®) blood counter analyzer; cytograms


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How to Cite this Article
Pubmed Style

D'Angelo G, Ceriani L, Hotz AM, Mazzola D, Ranalli R. Acute promyelocytic leukemia in four year-old child. A case report. Adv Lab Med Int. 2012; 2(3): 110-118.


Web Style

D'Angelo G, Ceriani L, Hotz AM, Mazzola D, Ranalli R. Acute promyelocytic leukemia in four year-old child. A case report. www.scopemed.org/?mno=22288 [Access: May 24, 2013].


AMA (American Medical Association) Style

D'Angelo G, Ceriani L, Hotz AM, Mazzola D, Ranalli R. Acute promyelocytic leukemia in four year-old child. A case report. Adv Lab Med Int. 2012; 2(3): 110-118.


Vancouver/ICMJE Style

D'Angelo G, Ceriani L, Hotz AM, Mazzola D, Ranalli R. Acute promyelocytic leukemia in four year-old child. A case report. Adv Lab Med Int. (2012), [cited May 24, 2013]; 2(3): 110-118.


Harvard Style

D'Angelo, G., Ceriani, L., Hotz, A. M., Mazzola, D. & Ranalli, R. (2012) Acute promyelocytic leukemia in four year-old child. A case report. Adv Lab Med Int, 2 (3), 110-118.


Turabian Style

D'Angelo, Guido, Lorena Ceriani, Anna Maria Hotz, Daniela Mazzola, and Roberta Ranalli. 2012. Acute promyelocytic leukemia in four year-old child. A case report. Advance Laboratory Medicine International, 2 (3), 110-118.


Chicago Style

D'Angelo, Guido, Lorena Ceriani, Anna Maria Hotz, Daniela Mazzola, and Roberta Ranalli. "Acute promyelocytic leukemia in four year-old child. A case report." Advance Laboratory Medicine International 2 (2012), 110-118.


MLA (The Modern Language Association) Style

D'Angelo, Guido, Lorena Ceriani, Anna Maria Hotz, Daniela Mazzola, and Roberta Ranalli. "Acute promyelocytic leukemia in four year-old child. A case report." Advance Laboratory Medicine International 2.3 (2012), 110-118. Print.


APA (American Psychological Association) Style

D'Angelo, G., Ceriani, L., Hotz, A. M., Mazzola, D. & Ranalli, R. (2012) Acute promyelocytic leukemia in four year-old child. A case report. Advance Laboratory Medicine International, 2 (3), 110-118.


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